How can I compare data from two quarters? What software can I use to do it parallelly side by side so I can compare them. What kind of factors can I take into consideration, I'm posting a sample data set pic
I am not sure what output you are looking for.
There are many ways to do it. You can do it by creating a measure in Power BI or in PowerPivot or just using Powerquery - below is an example.
PowerPivot and PowerQuery can both put the output into a pivot table in Excel if that's something you prefer.
Pick up city Q1 Q2
X Amount1 Amount 2
Y ... ...