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Questions tagged [bioinformatics]

The discipline at the crossroads of computing and the biological sciences, which involves organizing, maintaining, and analyzing data from such fields as molecular biology, genetics, and genomics

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21 views

How to split temporal sequences to sub-sequences in a meaningful yet unsupervised manner?

I have a biological process that undergoes some cellular event which I am observing. I have a series of events, with different temporal gaps between them. For example ...
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1answer
30 views

Bioinformatics widget

Why is there are no Volcano-plot or MA-plot in bioinformatics widget?
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20 views

What would happen if you trained an ML to detect artificially vs real generated voice data? [closed]

Voice data has been collected by big institituions for a really long time. Alexa and other technologies have since used them to make really human-sounding voices. What would happen if you had an ML ...
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56 views

Predictive model(s) to predict outputs at a future time $t_1$, given the predictor and output values at time points $t_0,t_1$?

Cross posted at- https://stats.stackexchange.com/questions/332759/predictive-models-to-predict-disease-at-a-future-time-t-1-given-the-predict, mentioning it to respect the guidelines. We've $N$ ...
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34 views

How to Implement Biological Neuron Activations in Artificial Neural Networks

In artificial neural networks, activation functions are used for neurons, i.e. the sigmoid activation: Which can be implemented in code as (in Python): ...
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2answers
4k views

Autoencoder for anomaly detection from feature vectors

I am trying to use an autoencoder (as described here https://blog.keras.io/building-autoencoders-in-keras.html#) for anomaly detection. I am using a ~1700 feature vector (rather than images, which ...
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4answers
11k views

Remove part of string in R

I have a table in R. It just has two columns and many rows. Each element is a string that contains some characters and some numbers. I need number part of the element. How can I have number part? For ...
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1answer
926 views

Feature selection for gene expression dataset

I am searching for a feature selection algorithm which selects features that are: relevant to discriminate groups of samples (for each sample a group label is provided) endowed with high variance ...
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1answer
32 views

Why is there such a wide range of prices for whole genome sequencing services?

Below is a list of labs around the country that offer genetic sequencing. What would be the reasons why they each cost a different amount if the end result is that you get a 90GB hard drive with 3+ ...
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68 views

Meta-analysis of public 16S data

I am trying to start a meta-analysis for which I want to extract some 16S-based information from public databases. Moreover, I want to relate this information with any metadata found in the associated ...
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1answer
261 views

R: Comparing dissimilarity between metabolic models with discrete wavelet transformation

I’m working on comparing bacteria metabolic models. Each model has a set of metabolites (around 2000) and their concentration for 200 time points. I’m in the process of comparing the models to cluster ...
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2answers
121 views

What kind of research can be done with genomic data?

It's well known that science has given us large amount of free accessible data, such as http://www.1000genomes.org and http://www.ncbi.nlm.nih.gov/genbank. How can we play around with the data and ...